Cat. No. 2891
Alternative Name: GR 38032
Chemical Name: 1,2,3,9-Tetrahydro-9-methyl-3-[(2-m
Biological ActivitySelective 5-HT3 receptor antagonist (Ki = 6.16 nM). Antiemetic; prevents emesis induced by cytotoxic drugs and radiation.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Youssefyeh et al (1992) Development of high-affinity 5-HT3 receptor antagonists. 1. Initial structure-activity relationship of novel benzamides. J.Med.Chem. 35 895. PMID: 1312602.
Ye et al (2001) Ondansetron: a selective 5-HT3 receptor antagonist and its applications in CNS-related disorders. CNS Drug Rev. 7 199. PMID: 11474424.
Ginawi et al (2005) Ondansetron, a selective antagonist, antagonizes methamphetamine-induced anorexia in mice. Pharmacol.Res. 51 255. PMID: 15661576.
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Keywords: Ondansetron hydrochloride, supplier, Selective, 5-HT3, antagonists, Serotonin, Receptors, GR38032
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November 15 - 19, 2014
Washington D.C., USA