Cat. No. 2843
Chemical Name: N,2,3,3-Tetramethylbicyclo[2.2.1]he
Biological ActivityNon-competitive nicotinic acetylcholine receptor antagonist. Displays antidepressant-like effects in mice.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Rabenstein et al (2006) The nicotinic antagonist mecamylamine has antidepressant-like effects in wild-type but not β2- or α7-nicotinic acetylcholine receptor subunit knockout mice. Psychopharmacol. 189 395.
Ostroumov et al (2007) Modeling study of mecamylamine block of muscle type acetylcholine receptors. Eur.Biophys.J. 37 393. PMID: 17938901.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: Mecamylamine hydrochloride, supplier, Non-competitive, nicotinic, receptors, antagonists, Acetylcholine, Non-Selective, Subtypes, nAChR
Find multiple products by catalog number
New Products in this Area
Allosteric agonist at α7 nAChRA 85380 dihydrochloride
High affinity and selective α4β2 agonistCC4
High affinity and subtype-selective α6β2 and α4β2 partial agonist
June 24 - 27, 2015
Booth Number: B11:25