Cat. No. 2843
Chemical Name: N,2,3,3-Tetramethylbicyclo[2.2.1]he
Biological ActivityNon-competitive nicotinic acetylcholine receptor antagonist. Displays antidepressant-like effects in mice.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Rabenstein et al (2006) The nicotinic antagonist mecamylamine has antidepressant-like effects in wild-type but not β2- or α7-nicotinic acetylcholine receptor subunit knockout mice. Psychopharmacol. 189 395.
Ostroumov et al (2007) Modeling study of mecamylamine block of muscle type acetylcholine receptors. Eur.Biophys.J. 37 393. PMID: 17938901.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: Mecamylamine hydrochloride, supplier, Non-competitive, nicotinic, receptors, antagonists, Acetylcholine, Non-Selective, Subtypes, nAChR
Find multiple products by catalog number
New Products in this Area
Partial agonist at α7 nAChRSIB 1508Y maleate
Potent agonist of α4β2, α2β4, α4β4 and α3β4 nACh receptorsIvermectin B1a-d2
Deuterated ivermectin B1a (Cat. No. 1260)
November 15 - 19, 2014
Washington D.C., USA