R&D Systems Inc. Tocris Bioscience Boston Biochem

Mecamylamine hydrochloride

Cat. No. 2843

Mecamylamine hydrochloride C11H21N.HCl [826-39-1]

Price and Availability

For Mecamylamine hydrochloride pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride

Biological Activity

Non-competitive nicotinic acetylcholine receptor antagonist. Displays antidepressant-like effects in mice.

Technical Data

M.Wt:
203.75
Formula:
C11H21N.HCl
Solubility:
Soluble to 100 mM in water and to 75 mM in DMSO
Storage:
Desiccate at RT
CAS No:
826-39-1

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet

References

Rabenstein et al (2006) The nicotinic antagonist mecamylamine has antidepressant-like effects in wild-type but not β2- or α7-nicotinic acetylcholine receptor subunit knockout mice. Psychopharmacol. 189 395.

Ostroumov et al (2007) Modeling study of mecamylamine block of muscle type acetylcholine receptors. Eur.Biophys.J. 37 393. PMID: 17938901.

If you know of a relevant citation for this product please let us know.

Keywords: Mecamylamine hydrochloride, supplier, Non-competitive, nicotinic, receptors, antagonists, Acetylcholine, Non-Selective, Subtypes, nAChR

Quick Order

Find multiple products by catalog number

divider line

Pain Research Product Guide

Pain Research Guide

Highlights over 280 products for Pain research. Request copy or view PDF today.

divider line

Nicotinic ACh Review

Nicotinic ACh Receptors Review

Written by Susan Wonnacott, an expert in the field. Updated in 2013. Reserve a copy today.

divider line

New Product Guide

NPG

Highlights over 130 new products added in the second half of 2013. Request a copy or view PDF today.

divider line

New Products in this Area

SIB 1508Y maleate

Potent agonist of α4β2, α2β4, α4β4 and α3β4 nACh receptors

Ivermectin B1a-d2

Deuterated ivermectin B1a (Cat. No. 1260)

Sign-up for new product e-alerts
divider line

Tocris Events

ICRS 2014

International Cannabinoid Research Society Symposium 2014

June 28 - July 3, 2014

Baveno, Italy