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Mecamylamine hydrochlorideCat. No. 2843 |
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Chemical Name: N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride |
Biological Activity
Non-competitive nicotinic acetylcholine receptor antagonist. Displays antidepressant-like effects in mice.Technical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
References
Rabenstein et al (2006) The nicotinic antagonist mecamylamine has antidepressant-like effects in wild-type but not β2- or α7-nicotinic acetylcholine receptor subunit knockout mice. Psychopharmacol. 189 395.
Ostroumov et al (2007) Modeling study of mecamylamine block of muscle type acetylcholine receptors. Eur.Biophys.J. 37 393. PMID: 17938901.
If you know of a relevant citation for this product please let us know.
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Keywords: Mecamylamine hydrochloride, supplier, Non-competitive, nicotinic, receptors, antagonists, Acetylcholine, Non-Selective, Subtypes, nAChR
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