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BIM 23052

Cat. No. 2842

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Biological Activity

Somatostatin sst₅ receptor agonist (K_i values are 7.3, 13.5, 31.3 and 141 nM for sst₅, sst₂, sst₁ and sst₄ receptors respectively). Stimulates gastric emptying following i.c. administration.

Technical Data

M.Wt:

1122.3

Formula:

C₆₁H₇₅N₁₁O₁₀

Sequence:

FFFWKTFT

(Modifications: Phe-1 = D-Phe, Trp-4 = D-Trp, Thr-8 = C-terminal amide)

Solubility:

Soluble to 2 mg/ml in 20% acetonitrile

Storage:

Store at -20°C

CAS No:

133073-82-2

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Safety Data Sheet: View Safety Data Sheet

References

Patel and Srikant (1994) Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5). Endocrinology 135 2814. PMID: 7988476.

Martinez et al (2000) Intracisternal injection of somatostatin receptor 5-preferring agonists induces a vagal cholinergic stimulation of gastric emptying in rats. J.Pharmacol.Exp.Ther. 293 1099. PMID: 10869415.

Nunn et al (2002) Pharmacological characterisation of the goldfish somatostatin sst5 receptor. Eur.J.Pharmacol. 436 173. PMID: 11858797.

If you know of a relevant citation for this product please let us know.

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