Levetiracetam

Cat. No. 2839

Levetiracetam C8H14N2O2 [102767-28-2]

Price and Availability

For Levetiracetam pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Alternative Names: Keppra, UCB L059

Chemical Name: (2S)-(2-Oxopyrrolidin-1-yl)butyramide

Biological Activity

Antiepileptic that displays distinctive properties from conventional antiepileptic drugs. Displays potent seizure protection in animal models of chronic epilepsy but lacks activity in acute seizure models. Binds synaptic vesicle protein 2A (SV2A) and inhibits Na+-dependent Cl-/HCO3- exchange.

Technical Data

M.Wt:
170.21
Formula:
C8H14N2O2
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
102767-28-2

Resources

Other Information

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Lynch et al (2004) The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proct.Natl.Acad.Sci. USA 101 9861.

Smedt et al (2007) Levetiracetam: the profile of a novel anticonvulsant drug - part I: preclinical data. CNS Drug Rev. 13 43. PMID: 17461889.

Ueda et al (2007) Effect of levetiracetam on molecular regulation of hippocampal glutamate and GABA transporters in rats with chronic seizures induced by amygdalar FeCl3 injection. Brain Res. 1151 55. PMID: 17408599.

If you know of a relevant citation for this product please let us know.

View Related Products by Product Action

Keywords: Levetiracetam, supplier, Anti-epileptic, binds, SV2A, Exocytosis, Endocytosis, Protein, Translocation, UCBL059, Tocris Bioscience, Translocation, Exocytosis & Endocytosis

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Product Guide

Highlights over 750 products for cancer research. Request copy or view PDF today.

divider line

New Products in this Area

CMPD101

Potent and selective GRK2/3 inhibitor

PMX 53c

Negative control for PMX 53 (Cat. No. 5473)

W 54011

High affinity C5a receptor antagonist

TDFA

PAD4 inhibitor

Sign-up for new product e-alerts
divider line

Bio-Techne Events

TOX EXPO

The Society of Toxicology's 55th Annual Meeting and ToxExpo

March 14 - 16, 2016

New Orleans, LA, USA