Cat. No. 2833
Chemical Name: 3β-Hydroxy-1αH,5αH-tropane-2β-carboxyli
Biological ActivityCompetitive inhibitor of monoamine neurotransmitter transporters. Inhibits dopamine (DAT), serotonin (SERT) and noradrenalin (NET) transporters with Ki values are 267, 392 and 872 nM respectively. Psychostimulant.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Fleckenstein et al (2000) Differential effects of stimulants on monoaminergic transporters: pharmacological consequences and implications for neurotoxicity. Eur.J.Pharmacol. 406 1. PMID: 11011026.
Torres et al (2003) Plasma membrane monoamine transporters: structure, regulation and function. Nat.Rev.Neurosci. 4 13. PMID: 12511858.
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Keywords: Cocaine hydrochloride, supplier, inhibitors, monoamine, transporters, noradrenalin, noradrenaline, transporters, NET, adrenergic, monoamine, neurotransmitter, DAT, dopamine, serotonin, SERT, 5-HT, reuptake, 5-Hydroxytryptamine