R&D Systems Inc. Tocris Bioscience Boston Biochem


Cat. No. 2807

EGTA C14H24N2O10 [67-42-5]

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Chemical Name: Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid

Biological Activity

Calcium chelator; protects against cell death caused by nitric oxide-induced calcium influx into nerve cells.

Technical Data

Soluble to 100 mM in 1M NaOH
Store at RT

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet


Boullerne et al (2001) Role of calcium in nitric oxide-induced cytotoxicity: EGTA protects mouse oligodendrocytes. J.Neurosci.Res. 63 124. PMID: 11169622.

Fisher et al (2004) Catalytic superoxide scavenging by metal complexes of the calcium chelator EGTA and contrast agent EHPG. Biochem.Biophy.Res.Comms. 323 163.

If you know of a relevant citation for this product please let us know.

Keywords: EGTA, supplier, Calcium, chelating, agent, Reagents, Signaling, Signalling, Agents, General, Ca2+

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Used to solubilize and denature proteins


Electrophoresis buffer

Sodium phosphate monobasic

Commonly used in biological assay buffers

Ponceau S Staining Solution

Stain used to detect protein bands after Western blotting


Reagent used in the measurement of cell proliferation


Dye used to stain cell nuclei

Guanidine Hydrochloride

Protein denaturant


Widely used in sample buffer preparation

Bromophenol Blue

Dye used in gel loading buffers

Bovine Serum Albumin

Widely used blocking agent for ELISA and blotting


Commonly used buffering agent

Boric acid

Widely used in buffers for electrophoresis

Sodium dodecyl sulphate solution

Detergent used in electrophoresis of proteins

Polyoxyethylenesorbitan monolaurate

Detergent used for protein extraction

Dulbecco's PBS

Buffered saline used in mammalian cell culture

Sodium phosphate dibasic

Commonly used in biological assay buffers

Potassium phosphate monobasic

Commonly used in biological assay buffers

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