Cat. No. 2671
Chemical Name: (11β,16α)-16,17-[Butylidenebis(oxy)]-
Biological ActivitySynthetic anti-inflammatory glucocorticoid that displays chemopreventive activity. Prevents formation of lung adenomas and adenocarcinomas in mice following inhalation or oral administration. Reverses DNA hypomethylation and modulates expression of cancer related genes.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Spencer et al (1995) Budesonide. A review of its pharmacological properties and therapeutic efficacy in inflammatory bowel disease. Drugs 50 854. PMID: 8586030.
Pereira et al (2006) Modulation by budesonide of DNA methylation and mRNA expression in mouse lung tumors. Int.J.Cancer 120 1150.
Wattenberg et al (2007) Chemoprevention of pulmonary carcinogenesis by aerosolized budesonide in female A/J mice. Cancer Res. 57 5489.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: Budesonide, supplier, Synthetic, glucocorticoid, anti-inflammatory, chemopreventive, Receptors
Find multiple products by catalog number
New Products in this Area
Selective estrogen receptor modulator (SERM)Rifaximin
Pregnane X receptor agonist; antibioticS 07662
Inverse agonist of the constitutive androstane receptor (CAR)
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.