WAY 170523

Cat No. 2633

WAY 170523 C33H31N3O7S [307002-73-9]

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Chemical Name: N-[2-[4-[[[2-[(Hydroxyamino)carbonyl]-4,6-dimethylpheny l](phenylmethyl)amino]sulfonyl]phenoxy]ethyl]-2-benzofu rancarboxamide

Biological Activity

Potent and selective inhibitor of MMP-13 (IC50 values are 17, 945, > 1000 and > 10000 nM for MMP-13, MMP-9, TACE and MMP-1 respectively).

Technical Data

M.Wt:
613.68
Formula:
C33H31N3O7S
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
>99 %
Storage:
Desiccate at RT
CAS No:
[307002-73-9]

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch

References

Chen et al (2000) Structure-based design of a novel, potent, and selective inhibitor for MMP-13 utilizing NMR spectroscopy and computer-aided molecular design. J.Am.Chem.Soc. 122 9648.

If you know of a useful citation for this product please let us know.

Keywords: WAY 170523, Potent, selective, inhibitors, MMP-13, Matrix, Metalloprotease, Matrixins, Metalloproteinase, MMP, Proteinases, Proteases, WAY170523

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