Cat. No. 4749
Biological ActivityCalcium sensing receptor (CaSR) agonist. Activates ERK1/2 signaling, intracellular calcium mobilization, and calcitonin secretion. Enhances osteogenic differentiation of mesenchymal stem cells.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Yang et al (2011) Strontium enhances osteogenic differentiation of mesenchymal stem cells and in vivo bone formation by activating Wnt/catenin signaling. Stem Cells 29 981. PMID: 21563277.
Thomsen et al (2012) Strontium is a biased agonist of the calcium-sensing receptor in rat medullary thyroid carcinoma 6-23 cells. J.Pharmacol.Exp.Ther. 343 638. PMID: 22942242.
If you know of a relevant citation for this product please let us know.
View Related Products by Product Action
Keywords: Strontium chloride, supplier, calcium, sensing, receptor, CaSR, agonists, ERK1/2, calcitonin, secretion, osteogenic, differentiation, stem, cells, Tocris Bioscience, Calcium-Sensing Receptor Agonists
Find multiple products by catalog number
New Products in this Area
Selective S1P2 allosteric agonistMRS 2905
Potent and selective P2Y14 receptor agonistTreprostinil
Potent prostacyclin (PGI2) analogS 18886
Potent thromboxane A2 (TP) antagonist
Win a $1,000 travel grant
Bio-Techne is offering 10 travel grants of $1,000 for FENS 2016.