CCT 031374 hydrobromide

Cat. No. 4675

CCT 031374 hydrobromide C23H19N3O.HBr [1219184-91-4]

Price and Availability

For CCT 031374 hydrobromide pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 1-[1,1'-Biphenyl]-4-yl-2-(2,3-dihydro-9H-imidazo[1,2-a]benzimidazol-9-yl)ethanone hydrobromide

Biological Activity

Inhibitor of TCF-dependent transcription. Blocks BIO-induced β-catenin stabilization; reduces nuclear and cytosolic β-catenin levels in mouse L-cells. Inhibits growth and reduces TCF-dependent transcription in SW480 colon carcinoma cells.

Technical Data

M.Wt:
434.33
Formula:
C23H19N3O.HBr
Solubility:
Soluble to 50 mM in DMSO
Purity:
>98 %
Storage:
Desiccate at RT
CAS No:
1219184-91-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Ewan et al (2010) A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription. Cancer Res. 70 5963. PMID: 20610623.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: CCT 031374 hydrobromide, supplier, CCT031374, hydrobromide, TCF, transcription, inhibitors, inhibits, beta-catenin, b-catenin, β-catenin, stabilization

Quick Order

Find multiple products by catalog number

divider line

New Product E-alerts

Sign up for email updates from Tocris

e-alerts

Enter your email address below to sign up to receive our email updates:

divider line

New Products in this Area

Foxy 5

Wnt5a peptide mimetic

Sign-up for new product e-alerts
divider line

Bio-Techne Events

ESM 2015

5th European Synapse Meeting

September 7 - 9, 2015

Bristol, UK