Cat. No. 4599
Chemical Name: 3,5-Dihydroxybenzoic acid
Biological ActivitySelective agonist of hydroxycarboxylic acid receptor 1 (HCA1, also known as GPR81) (EC50 ~150 μM). Inhibits lipolysis in wild-type mouse adipocytes. Displays minimal activity at HCA2 (at concentrations >10 mM) and no activity at HCA3, free fatty acid receptor (FFAR) 2 or FFAR3.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Liu et al (2012) 3,5-dihydroxybenzoic acid, a specific agonist for hydroxycarboxylic acid 1, inhibits lipolysis in adipocytes. J.Pharmacol.Exp.Ther. 341 794. PMID: 22434674.
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Keywords: 3,5-DHBA, supplier, gpr81, orphan, receptors, hca1, hydroxycarboxylic, acid, receptor, 1, hca1, selective, agonists
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