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3,5-DHBA

Cat. No. 4599

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Chemical Name: 3,5-Dihydroxybenzoic acid

Biological Activity

Selective agonist of hydroxycarboxylic acid receptor 1 (HCA1, also known as GPR81) (EC₅₀ ~150 μM). Inhibits lipolysis in wild-type mouse adipocytes. Displays minimal activity at HCA2 (at concentrations >10 mM) and no activity at HCA3, free fatty acid receptor (FFAR) 2 or FFAR3.

Technical Data

M.Wt:

154.12

Formula:

C₇H₆O₄

Solubility:

Soluble to 100 mM in water and to 100 mM in DMSO

Purity:

>99 %

Storage:

Store at RT

CAS No:

99-10-5

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Safety Data Sheet: View Safety Data Sheet

References

Liu et al (2012) 3,5-dihydroxybenzoic acid, a specific agonist for hydroxycarboxylic acid 1, inhibits lipolysis in adipocytes. J.Pharmacol.Exp.Ther. 341 794. PMID: 22434674.

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