Cat. No. 4483
Chemical Name: 7-Amino-1-cyclopropyl-3-ethyl-1,2,3
Biological ActivityInhibitor of eukaryotic elongation factor-2 (eEF-2) kinase (IC50 = 0.28 μM in enzymatic assay). Reduces eEF-2 phosphorylation with little effect on cancer cell growth.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Chen et al (2011) 1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) induces phosphorylation of eukaryotic elongation factor-2 (eEF2): a cautionary note on the anticancer mechanism of an eEF2 kinase inhibitor. J.Biol.Chem. 286 43951. PMID: 22020937.
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Keywords: A 484954, supplier, A484954, eukaryotic, elongation, factor-2, kinase, eef2k, inhibitors
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July 15, 2014