Cat. No. 4446
Chemical Name: 2-[Methyl(tetrahydro-1,1-dioxido-3-
Biological ActivityInhibitor of Krüppel-like factor 5 (KLF5) transcription factor (IC50 = 2.3 μM). Selectively active against colon cancer cells in a panel of 60 different cancer cell lines.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Bialkowska et al (2011) Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screening. Mol.Cancer Ther. 10 2043. PMID: 21885866.
If you know of a relevant citation for this product please let us know.
Keywords: CID 5951923, supplier, CID5951923, krueppel, kruppel, krüppel-like, factors, klf5, inhibitors, inhibits
Find multiple products by catalog number
New Products in this Area
YAP inhibitor; disrupts YAP-TEAD interactionsTC-S 7009
High affinity and selective HIF-2α inhibitorOltipraz
Nrf2 activatorHLM 006474
E2F transcription factor inhibitorCCG 203971
Inhibits the MRTF/SRF gene transcription pathway; antifibrotic agent
March 28 - April 1, 2015