R&D Systems Inc. Tocris Bioscience Boston Biochem

CID 5951923

Cat. No. 4446

CID 5951923 C16H18N2O7S [749872-43-3]

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Chemical Name: 2-[Methyl(tetrahydro-1,1-dioxido-3-thienyl)amino]-2-oxoethyl (E)-3-(3-nitrophenyl)prop-2-enoate

Biological Activity

Inhibitor of Krüppel-like factor 5 (KLF5) transcription factor (IC50 = 2.3 μM). Selectively active against colon cancer cells in a panel of 60 different cancer cell lines.

Technical Data

M.Wt:
382.39
Formula:
C16H18N2O7S
Solubility:
Soluble to 100 mM in DMSO
Purity:
>97 %
Storage:
Store at +4°C
CAS No:
749872-43-3

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Bialkowska et al (2011) Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screening. Mol.Cancer Ther. 10 2043. PMID: 21885866.

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Keywords: CID 5951923, supplier, CID5951923, krueppel, kruppel, krüppel-like, factors, klf5, inhibitors, inhibits

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