R&D Systems Inc. Tocris Bioscience Boston Biochem

Mephedrone hydrochloride

Cat. No. 4443

Mephedrone hydrochloride C11H15NO.HCl [1189726-22-4]

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Chemical Name: (±)-2-Methylamino-1-(4-methylphenyl)­propan-1-one hydrochloride

Biological Activity

Inhibits striatal dopamine uptake and hippocampal 5-HT uptake in synaptosomes (IC50 values are 467 and 558 nM respectively). Administration causes a decrease in dopamine and 5-HT transporter function. Synthetic CNS stimulant; brain penetrant.

Technical Data

M.Wt:
213.7
Formula:
C11H15NO.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
1189726-22-4

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Hadlock et al (2011) 4-methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse. J.Pharmacol.Exp.Ther. 339 530. PMID: 21810934.

If you know of a relevant citation for this product please let us know.

Keywords: Mephedrone hydrochloride, supplier, inhibitors, inhibits, dopamine, da, 5-ht, serotonin, uptake, transporters, brain, penetrant

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