R&D Systems Inc. Tocris Bioscience Boston Biochem

LF 11

Cat. No. 4421

LF 11 Phe-Gln-Trp-Gln-Arg-Asn-Ile-Arg-Lys-Val-Arg-NH2

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Biological Activity

Peptide based on the lipopolysaccharide (LPS)-binding region of human lactoferricin. Neutralizes LPS; displays antimicrobial activity against Gram-negative and Gram-positive bacteria. Analog lauryl-LF 11 (Cat. No. 4422) available.

Technical Data

M.Wt:
1529.81
Formula:
C69H112N26O14
Sequence:
FQWQRNIRKVR

(Modifications: Arg-11 = C-terminal amide)

Solubility:
Soluble to 2 mg/ml in 20% acetonitrile / water
Storage:
Store at -20°C
CAS No:
832729-13-2

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Andra et al (2005) Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem.J. 385 135. PMID: 15344905.

Japelj et al (2005) Structural origin of endotoxin neutralization and antimicrobial activity of a lactoferrin-based peptide. J.Biol.Chem. 280 16955. PMID: 15687491.

Sanchez-Gomez et al (2008) Comparative analysis of selected methods for the assessment of antimicrobial and membrane-permeabilizing activity: a case study for lactoferricin derived peptides. BMC Mirobiol. 11 196. PMID: 19014450.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: LF 11, supplier, LF11, lps, lipopolysaccharide, lactoferricin, antimicrobial, peptide, antibiotics

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