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26RFa

Cat. No. 4402

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Alternative Names: P518, QRFP

Biological Activity

Hypothalamic RFamide-related neuropeptide. Acts as a natural ligand of the orphan receptor GPR103. Exhibits orexigenic acitivity in mice upon central administration.

Technical Data

M.Wt:

2818.18

Formula:

C₁₂₇H₁₉₇N₃₇O₃₆

Sequence:

VGTALGSLAEELNGYNRKKGGFSFRF

(Modifications: Phe-26 = C-terminal amide)

Solubility:

Soluble to 1 mg/ml in water

Storage:

Store at -20°C

CAS No:

881640-56-8

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Safety Data Sheet: View Safety Data Sheet

References

Chartrel et al (2003) Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity. Proc.Natl.Acad.Sci.USA 100 15247. PMID: 14657341.

Kampe et al (2006) Effect of central administration of QRFP(26) peptide on energy balance and characterization of a second QRFP receptor in rat. Brain Res. 1119 133. PMID: 16996040.

Le Marec et al (2011) Structure-activity relationships of a series of analogues of the RFamide-related peptide 26RFa J.Med.Chem. 54 4806. PMID: 21623631.

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