Cat. No. 4394
Chemical Name: 3-Fluoro-5-(2-methyl-5-benzothiazolyl)-benzonitrile
Biological ActivityPotent negative allosteric modulator of mGlu5 (IC50 = 61 nM). Displays no activity at mGlu1-4 and mGlu7-8.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Lindsley et al (2011) (3-cyano-5-fluorophenyl)biaryl negative allosteric modulators of mGlu5: discovery of a new tool compound with activity in the OSS mouse model of addiction. ACS Chem.Neurosci. 2 471. PMID: 21927650.
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Keywords: VU 0360223, supplier, VU0360223, potent, antagonists, mglu5
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