R&D Systems Inc. Tocris Bioscience Boston Biochem

DLPC

Cat. No. 4378

DLPC C32H64NO8P [18194-25-7]

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Chemical Name: (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxododecyl)oxy]-3,5,9-trioxa-4-phosphaheneicosan-1-aminium-4-oxide

Biological Activity

Selective agonist of the orphan nuclear receptor LRH-1 (liver receptor homolog-1, NR5A2) in vitro. Induces bile acid biosynthetic enzymes; increases bile acid and decreases hepatic triglycerides and serum glucose. Exhibits antidiabetic effects.

Technical Data

M.Wt:
621.83
Formula:
C32H64NO8P
Solubility:
Soluble to 100 mM in ethanol
Storage:
Store at -20°C
CAS No:
18194-25-7

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Lee et al (2011) A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects. Nature 474 506. PMID: 21614002.

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View Related Products by Target

Keywords: DLPC, supplier, Dilauroyl, phosphatidylcholine, LRH-1, agonist, orphan, nuclear, receptor, agonists, NR5A2, saturated, fatty, acid, chain, liver, receptor, homolog, homologue

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