Cat. No. 4378
Chemical Name: (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxododecyl)oxy]-3,5,9-trioxa-4-phosphaheneicosan-1-aminium-4-oxide
Biological ActivitySelective agonist of the orphan nuclear receptor LRH-1 (liver receptor homolog-1, NR5A2) in vitro. Induces bile acid biosynthetic enzymes; increases bile acid and decreases hepatic triglycerides and serum glucose. Exhibits antidiabetic effects.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Lee et al (2011) A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects. Nature 474 506. PMID: 21614002.
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Keywords: DLPC, supplier, Dilauroyl, phosphatidylcholine, LRH-1, agonist, orphan, nuclear, receptor, agonists, NR5A2, saturated, fatty, acid, chain, liver, receptor, homolog, homologue
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