R&D Systems Inc. Tocris Bioscience Boston Biochem

Perindopril erbumine

Cat. No. 4302

Perindopril erbumine C19H32N2O5.C4H11N [107133-36-8]

Price and Availability

For Perindopril erbumine pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine salt

Biological Activity

Angiotensin-converting enzyme (ACE) inhibitor (IC50 = 1.05 nM). Brain penetrant. Suppresses the increase in hippocampal ACE activity and improves cognition in PS2APP-transgenic mice.

Technical Data

M.Wt:
441.6
Formula:
C19H32N2O5.C4H11N
Solubility:
Soluble to 50 mM in ethanol
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
107133-36-8

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Takai et al (2004) Significant target organs for hypertension and cardiac hypertrophy by angiotensin-converting enzyme inhibitors. Hypertens.Res. 27 213. PMID: 15080380.

Ceconi et al (2007) Angiotensin-converting enzyme (ACE) inhibitors have different selectivity for bradykinin binding sites of human somatic ACE. Eur.J.Pharmacol. 577 1. PMID: 17716647.

Dong et al (2011) Perindopril, a centrally active angiotensin-converting enzyme inhibitor, prevents cognitive impairment in mouse models of Alzheimer's disease. FASEB J. 25 2911. PMID: 21593435.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Perindopril erbumine, supplier, inhibits, angiotensin-converting, enzyme, ACE, inhibitor

Quick Order

Find multiple products by catalog number

divider line

New Product E-alerts

Sign up for email updates from Tocris

Sign-up for New Product E-alerts

Enter your email address below to sign up to receive our email updates:

divider line

New Products in this Area

Ramipril

Non-peptide, competitive angiotensin converting enzyme (ACE) inhibitor

Aprotinin

Competitive serine protease inhibitor

TCID

Selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor

2-MPPA

Selective glutamate carboxypeptidase II (GCP II) inhibitor; orally bioavailable

E 64

Potent and irreversible cysteine protease inhibitor

AEBSF

Broad spectrum, irreversible inhibitor of serine proteases

TC-E 5006

γ-secretase modulator; reduces Aβ42 levels

PTIQ

Potent MMP-3 expression inhibitor; neuroprotective

Sign-up for new product e-alerts
divider line

Twitter Updates

Follow @Tocris on Twitter

Follow us on Twitter!

Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.