R&D Systems Inc. Tocris Bioscience Boston Biochem

Perindopril erbumine

Cat. No. 4302

Perindopril erbumine C19H32N2O5.C4H11N [107133-36-8]

Price and Availability

For Perindopril erbumine pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine salt

Biological Activity

Angiotensin-converting enzyme (ACE) inhibitor (IC50 = 1.05 nM). Brain penetrant. Suppresses the increase in hippocampal ACE activity and improves cognition in PS2APP-transgenic mice.

Technical Data

M.Wt:
441.6
Formula:
C19H32N2O5.C4H11N
Solubility:
Soluble to 50 mM in ethanol
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
107133-36-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Takai et al (2004) Significant target organs for hypertension and cardiac hypertrophy by angiotensin-converting enzyme inhibitors. Hypertens.Res. 27 213. PMID: 15080380.

Ceconi et al (2007) Angiotensin-converting enzyme (ACE) inhibitors have different selectivity for bradykinin binding sites of human somatic ACE. Eur.J.Pharmacol. 577 1. PMID: 17716647.

Dong et al (2011) Perindopril, a centrally active angiotensin-converting enzyme inhibitor, prevents cognitive impairment in mouse models of Alzheimer's disease. FASEB J. 25 2911. PMID: 21593435.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Perindopril erbumine, supplier, inhibits, angiotensin-converting, enzyme, ACE, inhibitor

Quick Order

Find multiple products by catalog number

divider line

New Product E-alerts

Sign up for email updates from Tocris

e-alerts

Enter your email address below to sign up to receive our email updates:

divider line

New Products in this Area

Spautin 1

USP10 and USP13 inhibitor; inhibits autophagy

Sign-up for new product e-alerts
divider line

Bio-Techne Events

AACR 2015

AACR 2015

April 18 - 22, 2015

Philadelphia, PA

Booth: 2135