Cat. No. 4266
Alternative Name: CID 2950007
Chemical Name: 4-[4,5-Dihydro-5-(4-methoxyphenyl)-
Biological ActivityAllosteric inhibitor of Cdc42 GTPase (EC50 = 2.1 μM). Selective for Cdc42 over other members of the Rho GTPase family including Rac1, Rab2 and Rab7. Inhibits ovarian cancer cell migration in vitro.
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Certificate of Analysis / Safety Data Sheet
Surviladze et al (2010) A potent and selective inhibitor of Cdc42 GTPase. Probe Reports from the Molecular Libraries Program NBK5196. PMID: 21433396.
Hong et al (2013) Characterization of a Cdc42 GTPase Inhibitor and its Use as a Molecular Probe. J.Biol.Chem. Epub. PMID: 23382385.
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Keywords: ML 141, supplier, ML141, CID2950007, inhibits, cdc42, Rho, GTPase, inhibitor, inhibitors