Cat. No. 4204
Chemical Name: 2-(2-Pyridinyl)-4H-1,3-benzothiazin
Biological ActivityMacrophage migration inhibitory factor (MIF) binder (Kd = 68.6 nM). Activates antioxidant response element (ARE)-mediated gene expression. Suppresses oxidative stress-induced cardiomyocyte apoptosis in vitro. Cardioprotective.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Kimura et al (2010) BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitor factor regulates ARE-mediated gene expression. Chem.Biol. 17 1282. PMID: 21168764.
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Keywords: BTZO 1, supplier, BTZO1, mif, macrophage, migration, inhibitory, factors, binders, binds, cardioprotective