Cat. No. 4184
Chemical Name: (2R,4S)-4-[[[3,5-bis(Trifluoromethy
Biological ActivityInhibitor of cholesteryl ester transfer protein (CETP). Also impairs endothelial function in vivo; induces hypertension and inhibits acetylcholine-induced vasodilation in rabbit central ear artery.
Licensing InformationSold for research purposes under agreement from Pfizer Inc.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Forrest et al (2008) Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increasing circulating levels of aldosterone. Br.J.Pharmacol. 154 1465. PMID: 18536749.
Connelly et al (2010) Torcetrapib produces endothelial dysfunction independent of cholesteryl ester transfer protein inhibition. J.Cardiovascular Pharmacol. 55 459. PMID: 20051879.
If you know of a relevant citation for this product please let us know.
Keywords: Torcetrapib, supplier, hypercholesterolemia, inhibits, cholesteryl, ester, transferase, protein, CETP, impairs, endothelial, function
Find multiple products by catalog number
New Products in this Area
Inhibitor of eIF4E:eIF4G interactionJ 147
Neurotrophic compound. Reduces Aβ40 and Aβ42 levelsGPBAR-A
Bile acid receptor TGR5 (GPBA) agonistCRANAD 2
Near-infrared probe that detects Aβ40 aggregates
June 28 - July 3, 2014