R&D Systems Inc. Tocris Bioscience Boston Biochem

Alfacalcidol

Cat. No. 4159

Alfacalcidol C27H44O2 [41294-56-8]

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Alternative Name: 1-Hydroxycholecalciferol

Chemical Name: (1α,3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3-diol

Biological Activity

Metabolite and prodrug of vitamin D3 (Cat. No. 4156). Improves mechanical bone strength and bone mass; suppresses osteoclastic bone resorption in vivo.

Technical Data

M.Wt:
400.64
Formula:
C27H44O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
41294-56-8

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Shiraishi et al (2000) Alfacalcidol inhibits bone resorption and stmulates formation in an ovariectomized rat model of osteoporosis: Distinct actions from estrogen. Journal of Bone and Mineral Research. 15 770.

If you know of a relevant citation for this product please let us know.

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Keywords: Alfacalcidol, supplier, VDR, activators, vitamin, D3, analogue, analog, receptors

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