Cat. No. 4109
Chemical Name: N4-(7-Chloro-4-quinolinyl)-N1,N1-di
Biological ActivityAntimalarial drug. Inhibits cell growth and induces cell death in numerous cancer cell lines; inhibits cell proliferation and viability and induces apoptosis in 4T1 mouse breast cancer cells in vitro. Exhibits antimetastatic activity. Also inhibits autophagy via a mechanism distinct from that of 3-methyladenine (Cat. No. 3977).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Jiang et al (2010) Antitumor and antimetastatic activities of chloroquine diphosphate in a murine model of breast cancer. Biomed.Pharmacother. 64 609. PMID: 20888174.
Sasaki et al (2010) Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells. BMC Cancer 10 370. PMID: 20630104.
If you know of a relevant citation for this product please let us know.
Keywords: Chloroquine diphosphate, supplier, Chloroquine, diphosphate, antimalarial, antitumor, antimetastatic, autophagy, apoptosis
Find multiple products by catalog number
New Products in this Area
CARP-1 mimetic; proapoptoticNecrosulfonamide
Necroptosis inhibitorFK 866 hydrochloride
Nicotinamide phosphoribosyltransferase (NMPRTase) inhibitor; induces apoptosis; induces autophagy
June 28 - July 3, 2014