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AspirinCat. No. 4092 |
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Chemical Name: 2-Acetoxybenzoic acid |
Biological Activity
Inhibitor of cyclooxygenase (COX)-1. Blocks the production of prostaglandins and thromboxanes. Exhibits antiplatelet and antithrombotic activities. Displays anticancer effects in some solid tumors. One of the first described NSAID drugs.Certificate of Analysis / Safety Data Sheet
References
Sanduja et al (1991) Aspirin inhibits interleukin 1-induced prostaglandin H synthase expression in cultured endothelial cells. Proc.Natl.Acad.Sci. 15 88.
Baron (1995) Aspirin and cancer. Preventative Medicine 24 121.
Schror (1997) Aspirin and platelets: the antiplatelet action of aspirin and its role in thrombosis treatment and prophylaxis. Semin.Thromb.Hemost. 23 349. PMID: 9263351.
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Keywords: Aspirin, supplier, cyclooxygenase, inhibitors, antithrombotic, antiplatelet, NSAID, prostaglandin, H, synthase, blocks, thromboxane, synthesis
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