Cat. No. 4076
Chemical Name: 3,6-Dibromo-α-[(phenylamino)methyl]-
Biological ActivityNAMPT activator. Proneurogenic and neuroprotective. Protects newborn neurons in the dentate gyrus by mitigating cell death. Also enhances learning and memory in aged rats. Orally available and brain penetrant. Also revents doxorubicin-mediated toxicity in osteosarcoma cells and restores intracellular NAD levels.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Pieper et al (2010) Discovery of a proneurogenic, neuroprotective chemical. Cell 142 39. PMID: 20603013.
Wang et al (2014) P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage. Cell 158 1324. PMID: 25215490.
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Keywords: P7C3, supplier, P7C3, neuroprotective, neurogenesis, proneurogenic, Tocris Bioscience, NAMPT Activators