R&D Systems Inc. Tocris Bioscience Boston Biochem

Calcifediol

Cat. No. 4036

Calcifediol C27H44O2 [19356-17-3]

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Alternative Names: 25-Hydroxyvitamin D3, Calcidiol

Chemical Name: (εR,1R,3aS,4E,7aR)-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]octahydro-α,α,ε,7a-tetramethyl-1H-indene-1-pentanol

Biological Activity

Prohormone of calcitriol (Cat. No. 2551). Major circulating form of vitamin D. Suppresses PTH synthesis and secretion in bovine parathyroid cells (ED50 = 2 nM).

Technical Data

M.Wt:
400.64
Formula:
C27H44O2
Solubility:
Soluble in DMSO and in ethanol
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
19356-17-3

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

Ritter et al (2006) 25-hydroxyvitamin D3 suppresses PTH synthesis and secretion by bovine parathyroid cells. Kidney Int. 70 654. PMID: 16807549.

Rowling et al (2006) Megalin-mediated endocytosis of vitamin D binding protein correlates with 25-hydroxycholecalciferol actions in human mammary cells. J.Nutr. 136 2754. PMID: 17056796.

Fedirko et al (2010) Blood 25-hydroxyvitamin D3 concentrations and incident sporadic colorectal adenoma risk: a pooled case-control study. Am.J.Epidemiol. 172 489. PMID: 20650953.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: Calcifediol, supplier, major, circulating, forms, vitamin, D, cholecalciferol, 25-HydroxyvitaminD3, calcitriol, 1,25-DihydroxyvitaminD3

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