Betulinic acidCat No.
3906
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Price and Availability |
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Chemical Name: (+)-(3ß)-3-Hydroxylup-20(29)-en-28-oic acid |
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Biological Activity
Natural triterpenoid that displays anti-HIV and antitumor activity. Induces the production of reactive oxygen species (ROS) and activates NF-κB. Exhibits TRG5 agonist activity (EC50 = 1.04 μM).Technical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
References
Kashiwada et al (1996) Betulinic acid and dihydrobetulinic acid derivatives as potent anti-HIV agents. J.Med.Chem. 39 1016. Fulda (2008) Betulinic acid for cancer treatment and prevention. Int.J.Mol.Sci. 9 1096. Genet et al (2010) Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes. J.Med.Chem. 53 178.If you know of a useful citation for this product please let us know.
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Keywords: Betulinic acid, antitumor, anti-HIV, NFkappaB, NFkB, NFκB, TGR5, receptors, activators, activates, apoptosis, inducers
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