NAADP tetrasodium saltCat No.
3905
|
Price and Availability |
|
Alternative Name: NAADP Chemical Name: Nicotinic acid adenine dinucleotide phosphate tetrasodium salt |
|
Biological Activity
Ca2+ mobilizing agent. Initiates Ca2+ release via type 1 ryanodine receptor (RyR1) activation. Also regulates Ca2+ release from intracellular stores distinct from the endoplasmic reticulum (ER); displays affinity for two-pore channels (TPCs) which release Ca2+ from acidic organelles.Technical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
References
Calcraft et al (2009) NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature 459 596. Dammerman et al (2009) NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP agonist. Proc.Natl.Acad.Sci. 106 10678. Galione (2006) NAADP, a new intracellular messenger that mobilizes Ca2+ from acidic stores. Biochem.Soc.Transactions 34 922.If you know of a useful citation for this product please let us know.
Keywords: NAADP tetrasodium salt, general, Calcium, Signaling, Signalling, Agents, Ca2+, mobilization, beta-NAADP, β-NAADP, ryanodine, receptors
Buy Now / Print Quote
Find multiple products by catalog number
Print Quote Facility
Order via your purchasing department
It's now even easier to place orders via your purchasing department.
Simply add a product to your cart & click on the "Print Quote" button.
Calcium Imbalance and Neuroprotective Targets
Written by E. Besancon et al
'Calcium Imbalance and Neuro-protective Targets in Cerebral Ischemia & Brain Injury' highlights the key targets involved in stroke, trauma and neurodegeneration.
Signal Transduction Guide
A collection of more than 600 products for signal transduction research. View PDF today.
New Products in this Area
New Product Guide
Highlights over 250 new products added in 2009/10. Request a copy or view PDF today.