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UNC 0224Cat. No. 3861 |
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Chemical Name: 7-[3-(Dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-4-quinazolinamine |
Biological Activity
Potent inhibitor of G9a histone lysine methyltransferase (IC50 = 15 nM).Certificate of Analysis / Safety Data Sheet
References
Liu et al (2009) Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a. J.Med.Chem. 52 7950. PMID: 19891491.
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Keywords: UNC 0224, supplier, UNC0224, potent, inhibitors, inhibits, histone, lysine, methyltransferases, htmase, G9a, epigenetics
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