R&D Systems Inc. Tocris Bioscience Boston Biochem

RuBi-Nicotine

Cat. No. 3855

RuBi-Nicotine C40H44Cl2N8Ru [1256362-30-7]

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Chemical Name: Bis(2,2'-bipyridine-N,N')bis(S-nicoti­ne-N1) ruthenium(2+) dichloride

Biological Activity

Ruthenium-bisbipyridine-caged nicotine, excitable by irradiation with visible light. Undergoes rapid photolysis to release nicotine (< 20 ns); exhibits a high quantum yield. Induces action potential propagation in Retzius neurons of leech ganglia with no detectable toxicity at a concentration of 1 mM.

Licensing Information

Sold under license from CHEMCAGE, patent 8063216

Technical Data

M.Wt:
808.81
Formula:
C40H44Cl2N8Ru
Solubility:
Soluble to 50 mM in water
Storage:
Store at -20°C
CAS No:
1256362-30-7

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

References

Filevich et al (2010) A caged nicotine with nanosecond range kinetics and visible light sensitivity. J.Inorg.Biochem. 104 1248. PMID: 20825994.

If you know of a relevant citation for this product please let us know.

Keywords: RuBi-Nicotine, supplier, RuBiNicotine, caged, compounds, nicotinics, cholinergics, acetylcholine, receptors, nAChRs, agonist, excitatory

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