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RuBi-Nicotine

Cat. No. 3855

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Chemical Name: Bis(2,2'-bipyridine-N,N')bis(S-nicotine-N1) ruthenium(2⁺) dichloride

Biological Activity

Ruthenium-bisbipyridine-caged nicotine, excitable by irradiation with visible light. Undergoes rapid photolysis to release nicotine (< 20 ns); exhibits a high quantum yield. Induces action potential propagation in Retzius neurons of leech ganglia with no detectable toxicity at a concentration of 1 mM.

Licensing Information

Sold under license from CHEMCAGE, patent 8063216

Technical Data

M.Wt:

808.81

Formula:

C₄₀H₄₄Cl₂N₈Ru

Solubility:

Soluble to 50 mM in water

Storage:

Store at -20°C

CAS No:

1256362-30-7

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Safety Data Sheet: View Safety Data Sheet

References

Filevich et al (2010) A caged nicotine with nanosecond range kinetics and visible light sensitivity. J.Inorg.Biochem. 104 1248. PMID: 20825994.

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