Cat. No. 3805
Alternative Name: AG-EE 623ZW
Chemical Name: 2-Ethoxy-4-[2-[[(1S)-3-methyl-1-[2-
Biological ActivityKir6 (KATP) channel blocker that binds with high affinity for SUR1 when co-expressed with Kir6.2 (Kd = 0.42 nM). Antidiabetic glucose regulator with hypoglycaemic effect in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Mark and Grell (1997) Hypoglycaemic effects of the novel antidiabetic agent repaglinide in rats and dogs. Br.J.Pharmacol. 121 1597. PMID: 9283692.
Hansen et al (2005) Kir6.2-dependent high-affinity repaglinide binding to β-cell KATP channels. Br.J.Pharmacol. 144 551. PMID: 15678092.
If you know of a relevant citation for this product please let us know.
Keywords: Repaglinide, supplier, K+, channel, pore, blockers, KATP, Blocks, SUR1, KIR6, Kir6.2, sulphonylurea, receptor, inward, rectifier
Find multiple products by catalog number
New Products in this Area
Potent KCa3.1 blockerBDS I
Potent and reversible Kv3.4 potassium channel blocker; neuroprotectiveAgitoxin 2
Potent Shaker K+ channel blocker
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.