CP 135807

Cat No. 3783new product

CP 135807 C19H21N5O2 [151272-90-1]

Price and Availability

For CP 135807 pricing & availability please select your country from the drop down menu:
Submit

Chemical Name: 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-N-(3-nitro-2-p yridinyl)-1H-indol-5-amine

Biological Activity

Selective 5-HT1D receptor agonist. Produces dose-dependent decreases in extracellular 5-HT concentration.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc

Technical Data

M.Wt:
351.4
Formula:
C19H21N5O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at +4°C
CAS No:
[151272-90-1]

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch

References

Hertel et al (1999) The antipsychotic drug risperidone interacts with auto- and hetero-receptors regulating serotonin output in the rat frontal cortex. Neuropharmacology 38  1175. Mansbach et al (1996) CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon. Psychopharmacology 128 313. Rollema et al (1996) Combined administration of a 5-hydroxytryptamine (5-HT)1D antagonist and a 5-HT reuptake inhibitor synergistically increases 5-HT release in guinea pig hypothalamus in vivo. J.Neurochem. 67 2204.

If you know of a useful citation for this product please let us know.

View Related Products by Target

Keywords: CP 135807, selective, 5-HT, serotonin, 5-HT1D, receptors, agonists, Pfizer

Buy Now / Print Quote

Find multiple products by catalog number


divider line

Print Quote Facility

Order via your purchasing department

Print Quote Facility

It's now even easier to place orders via your purchasing department.

Simply add a product to your cart & click on the "Print Quote" button.

more
divider line

GPCRs and Signalling Networks

Written by M.J. Marinissen

GPCR Poster

'G-Protein-coupled Receptors and Signalling Networks' summarizes the intricate network of intracellular signalling pathways involved in GPCR function.

request
divider line

7-TM Receptor Signalling

Written by T. Kenakin et al

7-TM Poster

'Seven Transmembrane Receptor Signalling' highlights the multiple behaviors of 7-TMs including G-protein-dependent and -independent signaling as well as the concept of collateral efficacy

request
divider line

New Products in this Area

NAD 299

Selective, high affinity 5-HT1A receptor antagonist

Donitriptan hydrochloride

5-HT1B/1D agonist

CP 135807

Selective 5-HT1D agonist

Eletriptan hydrobromide

Orally active, selective 5-HT1B/1D agonist

Sign-up for new product e-alerts
divider line

Special Offer

25% discount* on selected Tocris products:


*Terms and Conditions

To view more special offers....

submit