CP 135807Cat No.
3783
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Price and Availability |
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Chemical Name: 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-N-(3-nitro-2-p yridinyl)-1H-indol-5-amine |
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Biological Activity
Selective 5-HT1D receptor agonist. Produces dose-dependent decreases in extracellular 5-HT concentration.Licensing Information
Sold for research purposes under agreement from Pfizer IncTechnical Data
M.Wt:The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
References
Hertel et al (1999) The antipsychotic drug risperidone interacts with auto- and hetero-receptors regulating serotonin output in the rat frontal cortex. Neuropharmacology 38 1175. Mansbach et al (1996) CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon. Psychopharmacology 128 313. Rollema et al (1996) Combined administration of a 5-hydroxytryptamine (5-HT)1D antagonist and a 5-HT reuptake inhibitor synergistically increases 5-HT release in guinea pig hypothalamus in vivo. J.Neurochem. 67 2204.If you know of a useful citation for this product please let us know.
Keywords: CP 135807, selective, 5-HT, serotonin, 5-HT1D, receptors, agonists, Pfizer
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