Cat. No. 3783
Chemical Name: 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-N-(3-nitro-2-pyridinyl)-1H-indol-5-amine
Biological ActivitySelective 5-HT1D receptor agonist. Produces dose-dependent decreases in extracellular 5-HT concentration.
Licensing InformationSold for research purposes under agreement from Pfizer Inc.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Mansbach et al (1996) CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon. Psychopharmacology 128 313. PMID: 8972551.
Rollema et al (1996) Combined administration of a 5-hydroxytryptamine (5-HT)1D antagonist and a 5-HT reuptake inhibitor synergistically increases 5-HT release in guinea pig hypothalamus in vivo. J.Neurochem. 67 2204. PMID: 8863532.
Hertel et al (1999) The antipsychotic drug risperidone interacts with auto- and hetero-receptors regulating serotonin output in the rat frontal cortex. Neuropharmacology 38 1175. PMID: 10462130.
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Keywords: CP 135807, supplier, selective, 5-HT, serotonin, 5-HT1D, receptors, agonists, Pfizer, CP135807
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June 21, 2013