R&D Systems Inc. Tocris Bioscience Boston Biochem

GSK 264220A

Cat. No. 3752

GSK 264220A C17H21N3O4S [685506-42-7]

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Chemical Name: N-[2-Methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenylurea

Biological Activity

Endothelial lipase and lipoprotein lipase inhibitor (IC50 values are 0.13 and 0.10 μM respectively).

Technical Data

M.Wt:
363.43
Formula:
C17H21N3O4S
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
>98 %
Storage:
Store at +4°C
CAS No:
685506-42-7

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Keller et al (2008) A high-throughput screen for the endothelial lipase using HDL as substrate. J.Biomol.Screen. 13 468. PMID: 18566479.

Goodman et al (2009) Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors. Bioorg.Med.Chem.Letts. 19 27.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: GSK 264220A, supplier, GSK264220A, endothelial, lipase, lipoprotein, lipases, inhibitors

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