Cat. No. 3752
Chemical Name: N-[2-Methyl-5-(1-piperidinylsulfony
Biological ActivityEndothelial lipase and lipoprotein lipase inhibitor (IC50 values are 0.13 and 0.10 μM respectively).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Keller et al (2008) A high-throughput screen for the endothelial lipase using HDL as substrate. J.Biomol.Screen. 13 468. PMID: 18566479.
Goodman et al (2009) Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors. Bioorg.Med.Chem.Letts. 19 27.
If you know of a relevant citation for this product please let us know.
Keywords: GSK 264220A, supplier, GSK264220A, endothelial, lipase, lipoprotein, lipases, inhibitors
Find multiple products by catalog number
New Products in this Area
Highly selective and potent monoacylglycerol lipase (MAGL) inhibitorPF 8380
Potent autotaxin inhibitorAPY 29
Inhibits IRE1α autophosphorylation; activates IRE1α endoribonuclease activity
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.