BYK 204165

Cat No. 3734new product

BYK 204165 C15H12N2O2 [1104546-89-5]

Price and Availability

For BYK 204165 pricing & availability please select your country from the drop down menu:
Submit

Chemical Name: 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoqu inolinedione

Biological Activity

Potent and selective poly(ADP-ribose) polymerase (PARP)-1 inhibitor (pIC50 values are 5.38 and 7.35 for PARP-2 and PARP-1 respectively).

Technical Data

M.Wt:
252.27
Formula:
C15H12N2O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
>99 %
Storage:
Desiccate at +4°C
CAS No:
[1104546-89-5]

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch

References

Eltze et al (2008) Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors. Mol.Pharmacol. 74 1587.

If you know of a useful citation for this product please let us know.

View Related Products by Target

Keywords: BYK 204165, BYK204165, PARP1, poly(ADP-ribose), polymerases, selective, inhibitors

Buy Now / Print Quote

Find multiple products by catalog number


divider line

Print Quote Facility

Order via your purchasing department

Print Quote Facility

It's now even easier to place orders via your purchasing department.

Simply add a product to your cart & click on the "Print Quote" button.

more
divider line

Signal Transduction Guide

Signal Transduction Guide

A collection of more than 600 products for signal transduction research. View PDF today.

request
divider line

Cancer Research Guide

Cancer Research Guide

Highlights over 400 products for cancer research. Request a copy or view PDF today.

request
divider line

Calcium Imbalance and Neuroprotective Targets

Written by E. Besancon et al

Neuroprotection Poster

'Calcium Imbalance and Neuro-protective Targets in Cerebral Ischemia & Brain Injury' highlights the key targets involved in stroke, trauma and neurodegeneration.

request
divider line

New Products in this Area

BYK 204165

Selective PARP-1 inhibitor

UPF 1069

PARP-2 inhibitor

Sign-up for new product e-alerts
divider line

Special Offer

25% discount* on selected Tocris products:


*Terms and Conditions

To view more special offers....

submit