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BYK 204165Cat No.
3734
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Price and Availability |
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Chemical Name: 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoqu inolinedione |
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Biological Activity
Potent and selective poly(ADP-ribose) polymerase (PARP)-1 inhibitor (pIC50 values are 5.38 and 7.35 for PARP-2 and PARP-1 respectively).Technical Data
M.Wt:252.27
Formula:C15H12N2O2
Solubility:Soluble to 100 mM in DMSO
Purity: >99 %
Storage:Desiccate at +4°C
CAS No:[1104546-89-5]
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch
References
Eltze et al (2008) Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors. Mol.Pharmacol. 74 1587.If you know of a useful citation for this product please let us know.
Keywords: BYK 204165, BYK204165, PARP1, poly(ADP-ribose), polymerases, selective, inhibitors
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