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Imiquimod

Cat No. 3700

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Alternative Name: R 837

Chemical Name: 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine

Biological Activity

Immunomodulator that displays antiviral and antitumor activity. Acts as a Toll-like receptor 7 (TLR-7) agonist; stimulates proinflammatory cytokine production and activates NF-κB.

Technical Data

M.Wt:

240.3

Formula:

C₁₄H₁₆N₄

Solubility:

Soluble to 10 mM in DMSO

Purity:

>99 %

Storage:

Store at +4°C

CAS No:

[99011-02-6]

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Resources

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch

Material Safety Data Sheet: View current batch

References

Syed et al (2001) A review of the applications of imiquimod: a novel immune response modifier. Exp. Opin.Pharmacother. 2 877. Schon and Schon (2007) The antitumoral mode of action of imiquimod and other imidazoquinolines. Curr.Med.Chem. 14 681. Averett et al (2007) The pharmacology of endosomal TLR agonists in viral disease. Biochem.Soc.Trans. 35 1468.

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