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Home »
Pharmacology » Ion Channels » Ligand-gated Ion Channels » GABAA and GABAC Receptors » GABAA Receptors » Allopregnanolone
AllopregnanoloneCat No. 3653 |
Price and Availability |
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Alternative Name: 3 Chemical Name: (3a,5a)-3-Hydroxy-pregnan-20-one |
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Biological Activity
GABAA receptor positive allosteric modulator. Neuroactive steroid.Technical Data
M.Wt:318.49
Formula:C21H34O2
Solubility:Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage:Store at RT
CAS No:[516-54-1]
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch
References
Puia et al (1990) Neurosteroids act on recombinant human GABAA receptors. Neuron 4 759. Belelli and Lambert (2005) Neurosteroids: endogenous regulators of the GABAA receptor. Nat.Rev.Neurosci. 6 565. Agis-Balboa et al (2006) Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis. Proc.Natl.Acad.Sci.USA 103 14602.If you know of a useful citation for this product please let us know.
Keywords: Allopregnanolone, GABAA, receptors, positive, allosteric, modulators, neuroactive, steroid
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