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Home »
Pharmacology » Ion Channels » Ligand-gated Ion Channels » GABAA and GABAC Receptors » GABAA Receptors » Pregnanolone
PregnanoloneCat No. 3652 |
Price and Availability |
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Chemical Name: (3a,5b)-3-Hydroxy-pregnan-20-one |
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Biological Activity
GABAA receptor positive allosteric modulator. Neuroactive steroid.Technical Data
M.Wt:318.49
Formula:C21H34O2
Solubility:Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage:Store at RT
CAS No:[128-20-1]
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch
References
Harrison et al (1987) Structure-activity relationships for steroid interaction with the g-aminobutyric acidA receptor complex. J.Pharmacol.Exp.Ther. 241 346. Morris et al (1999) Differential modulation of the g-aminobutyric acid type C receptor by neuroactive steroids. Mol.Pharmacol. 56 752.If you know of a useful citation for this product please let us know.
Keywords: Pregnanolone, GABAA, receptors, positive, allosteric, modulators, neuroactive, steroid
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