Pregnanolone

Cat No. 3652

Pregnanolone C21H34O2 [128-20-1]

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Chemical Name: (3a,5b)-3-Hydroxy-pregnan-20-one

Biological Activity

GABAA receptor positive allosteric modulator. Neuroactive steroid.

Technical Data

M.Wt:
318.49
Formula:
C21H34O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage:
Store at RT
CAS No:
[128-20-1]

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch
Material Safety Data Sheet: View current batch

References

Harrison et al (1987) Structure-activity relationships for steroid interaction with the g-aminobutyric acidA receptor complex. J.Pharmacol.Exp.Ther. 241 346. Morris et al (1999) Differential modulation of the g-aminobutyric acid type C receptor by neuroactive steroids. Mol.Pharmacol. 56 752.

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Keywords: Pregnanolone, GABAA, receptors, positive, allosteric, modulators, neuroactive, steroid

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