R&D Systems Inc. Tocris Bioscience Boston Biochem

cAMPS-Sp, triethylammonium salt

Cat. No. 1333

cAMPS-Sp, triethylammonium salt C10H12N5O5PS.C6H15N [93602-66-5]

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Chemical Name: (S)-Adenosine, cyclic 3',5'-(hydrogenphosphorothioate) triethylammonium

Biological Activity

Cell-permeable cAMP analog that activates cAMP receptor proteins such as PKA and cAMP-regulated guanine nucleotide exchange factor. Enantiomer cAMPS-Rp, triethylammonium salt (Cat. No. 1337) also available.

Technical Data

M.Wt:
446.46
Formula:
C10H12N5O5PS.C6H15N
Solubility:
Soluble to 100 mM in water
Purity:
>98 %
Storage:
Desiccate at -20°C
CAS No:
93602-66-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

O'Brian et al (1982) A kinetic study of interactions of (Rp)- and (Sp)-adenosine cyclic 3',5'-phosphorothioates with type II bovine cardiac muscle adenosine cyclic 3',5'-phosphate dependent protein kinase. Biochemistry 21 4371. PMID: 6289880.

Dostmann et al (1990) Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates. J.Biol.Chem. 265 10484. PMID: 2162349.

Kawasaki et al (1998) A family of cAMP-binding proteins that directly activate Rap1. Science 282 2275. PMID: 9856955.

Lin et al (2006) Ethanol inhibition of NMDA-induced responses and actute tolerance to the inhibition in rat rostral ventrolateral medulla in vivo: Involvement of cAMP-dependent protein kinases. Neuropharmacology 51 747. PMID: 16806304.

If you know of a relevant citation for this product please let us know.

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Keywords: cAMPS-Sp, triethylammonium salt, supplier, Cell-permeable, cAMP, Cyclic, adenosines, Monophosphate

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