R&D Systems Inc. Tocris Bioscience Boston Biochem

cAMPS-Sp, triethylammonium salt

Cat. No. 1333

cAMPS-Sp, triethylammonium salt C10H12N5O5PS.C6H15N [93602-66-5]

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Chemical Name: (S)-Adenosine, cyclic 3',5'-(hydrogenphosphorothioate) triethylammonium

Biological Activity

Cell-permeable cAMP analog that activates cAMP receptor proteins such as PKA and cAMP-regulated guanine nucleotide exchange factor. Enantiomer cAMPS-Rp, triethylammonium salt (Cat. No. 1337) also available.

Technical Data

M.Wt:
446.46
Formula:
C10H12N5O5PS.C6H15N
Solubility:
Soluble to 100 mM in water
Purity:
>98 %
Storage:
Desiccate at -20°C
CAS No:
93602-66-5

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

References

O'Brian et al (1982) A kinetic study of interactions of (Rp)- and (Sp)-adenosine cyclic 3',5'-phosphorothioates with type II bovine cardiac muscle adenosine cyclic 3',5'-phosphate dependent protein kinase. Biochemistry 21 4371. PMID: 6289880.

Dostmann et al (1990) Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates. J.Biol.Chem. 265 10484. PMID: 2162349.

Kawasaki et al (1998) A family of cAMP-binding proteins that directly activate Rap1. Science 282 2275. PMID: 9856955.

Lin et al (2006) Ethanol inhibition of NMDA-induced responses and actute tolerance to the inhibition in rat rostral ventrolateral medulla in vivo: Involvement of cAMP-dependent protein kinases. Neuropharmacology 51 747. PMID: 16806304.

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Keywords: cAMPS-Sp, triethylammonium salt, supplier, Cell-permeable, cAMP, Cyclic, adenosines, Monophosphate

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