(R)-(-)-Deprenyl hydrochlorideCat. No. 1095 |
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Alternative Name: Selegiline Chemical Name: (R)-(-)-N-α-Dimethyl-N-2-propynylbenzeneethanamine hydrochloride |
Biological Activity
Selective inhibitor of monoamine oxidase B (MAO-B).Certificate of Analysis / Safety Data Sheet
References
Merck Index 12 8569.
Gerlach et al (1992) The molecular pharmacology of L-deprenyl. Eur.J.Pharmacol. 226 97. PMID: 1639115.
Kotake et al (1998) Deprenyl decreases an endogenous parkinsonism-inducing compound, 1-benzyl-1,2,3,4-tetrahydroisoquinoline in mice: in vivo and in vitro studies. Brain Res. 787 341. PMID: 9518683.
Mercuri et al (1998) Modification of levodopa responses by deprenyl (selegiline): an electrophysiological and behavioural study in the rat relevant to Parkinson's disease. Ann.Neurol. 43 613. PMID: 9585355.
Kaseda et al (1999) Effect of selegeline on dopamine concentration in the striatum of a primate. Brain Res. 815 44. PMID: 9974121.
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Keywords: (R)-(-)-Deprenyl hydrochloride, supplier, MAO-B, inhibitors, Monoamine, Oxygenases, Oxidases
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