R&D Systems Inc. Tocris Bioscience Boston Biochem

(R)-(-)-Deprenyl hydrochloride

Cat. No. 1095

(R)-(-)-Deprenyl hydrochloride C13H17N.HCl [14611-52-0]

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Alternative Name: Selegiline

Chemical Name: (R)-(-)-N-α-Dimethyl-N-2-propynylben­zeneethanamine hydrochloride

Biological Activity

Selective inhibitor of monoamine oxidase B (MAO-B).

Technical Data

M.Wt:
223.74
Formula:
C13H17N.HCl
Solubility:
Soluble to 100 mM in water
Purity:
>99 %
Storage:
Store at RT
CAS No:
14611-52-0

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Merck Index 12 8569.

Gerlach et al (1992) The molecular pharmacology of L-deprenyl. Eur.J.Pharmacol. 226 97. PMID: 1639115.

Kotake et al (1998) Deprenyl decreases an endogenous parkinsonism-inducing compound, 1-benzyl-1,2,3,4-tetrahydroisoquinoline in mice: in vivo and in vitro studies. Brain Res. 787 341. PMID: 9518683.

Mercuri et al (1998) Modification of levodopa responses by deprenyl (selegiline): an electrophysiological and behavioural study in the rat relevant to Parkinson's disease. Ann.Neurol. 43 613. PMID: 9585355.

Kaseda et al (1999) Effect of selegeline on dopamine concentration in the striatum of a primate. Brain Res. 815 44. PMID: 9974121.

If you know of a relevant citation for this product please let us know.

Keywords: (R)-(-)-Deprenyl hydrochloride, supplier, MAO-B, inhibitors, Monoamine, Oxygenases, Oxidases

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