R&D Systems Inc. Tocris Bioscience Boston Biochem

(R)-(-)-Deprenyl hydrochloride

Cat. No. 1095

(R)-(-)-Deprenyl hydrochloride C13H17N.HCl [14611-52-0]

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Alternative Name: Selegiline

Chemical Name: (R)-(-)-N-α-Dimethyl-N-2-propynylbenzeneethanamine hydrochloride

Biological Activity

Selective inhibitor of monoamine oxidase B (MAO-B).

Technical Data

M.Wt:
223.74
Formula:
C13H17N.HCl
Solubility:
Soluble to 100 mM in water
Purity:
>99 %
Storage:
Store at RT
CAS No:
14611-52-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Merck Index 12 8569.

Gerlach et al (1992) The molecular pharmacology of L-deprenyl. Eur.J.Pharmacol. 226 97. PMID: 1639115.

Kotake et al (1998) Deprenyl decreases an endogenous parkinsonism-inducing compound, 1-benzyl-1,2,3,4-tetrahydroisoquinoline in mice: in vivo and in vitro studies. Brain Res. 787 341. PMID: 9518683.

Mercuri et al (1998) Modification of levodopa responses by deprenyl (selegiline): an electrophysiological and behavioural study in the rat relevant to Parkinson's disease. Ann.Neurol. 43 613. PMID: 9585355.

Kaseda et al (1999) Effect of selegeline on dopamine concentration in the striatum of a primate. Brain Res. 815 44. PMID: 9974121.

If you know of a relevant citation for this product please let us know.

Keywords: (R)-(-)-Deprenyl hydrochloride, supplier, MAO-B, inhibitors, Monoamine, Oxygenases, Oxidases, parkinson's, parkinsons

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