Cat. No. 1257
Chemical Name: 22-Oxovincaleukoblastine
Biological ActivityAnticancer agent; microtubule disrupter. Induces apoptosis in human lymphoma cells.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Jordan et al (1985) Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitro. Cancer Res. 45 2741. PMID: 3986806.
Takano et al (1993) Apoptosis induced by microtubule disrupting drugs in cultured human lymphoma cells. Inhibitory effects of phorbol ester and zinc sulphate. Pathol.Res.Pract. 189 197. PMID: 8321748.
Wang et al (1999) The effect of antimicrotubule agents on signal transduction pathways of apoptosis. Cancer Chemother.Pharmacol. 44 355. PMID: 10501907.
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Keywords: Vincristine sulfate, supplier, Disrupts, microtubules, Tau, Tubulin, Mitosis