4-P-PDOT

Cat. No. 1034

4-P-PDOT C19H21NO [620170-78-7]

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Alternative Name: AH 024

Chemical Name: cis-4-Phenyl-2-propionamidotetralin

Biological Activity

Melatonin receptor antagonist, >300-fold selective for the MT2 (vs MT1) subtype.

Technical Data

M.Wt:
279.38
Formula:
C19H21NO
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
>99 %
Storage:
Store at RT
CAS No:
620170-78-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Dubocovich et al (1995) Melatonin receptors: are there multiple subtypes? TiPS 16 50. PMID: 7762083.

Dubocovich et al (1997) Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroceptor. Naunyn Schmiedebergs Arch.Pharmacol. 355 365. PMID: 9089668.

If you know of a relevant citation for this product please let us know.

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Keywords: 4-P-PDOT, supplier, MT2, antagonists, Receptors, Melatonin, AH024, Tocris Bioscience, Melatonin Receptor Antagonists

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