NBQX disodium salt

Cat. No. 1044

NBQX disodium salt C12H6N4O6SNa2 [479347-86-9]

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Chemical Name: 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide disodium salt

Biological Activity

Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo. More water soluble disodium salt of NBQX (Cat. No. 0373). Also available as part of the AMPA Receptor Tocriset™.

Licensing Information

Sold with the permission of Novo Nordisk A/S

Technical Data

Soluble to 100 mM in water
>98 %
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Gill et al (1992) The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline (NBQX) in a rat focal ischaemia model. Brain Res. 580 35. PMID: 1504814.

Zeman and Lodg (1992) Pharmacological characterization of non-NMDA subtypes of glutamate receptors in the neonatal rat hemisected spinal cord in vitro. Br.J.Pharmacol. 106 367. PMID: 1382781.

Sheardown et al (1993) The pharmacology of AMPA receptors and their antagonists. Stroke 24 146. PMID: 7504337.

Namba et al (1994) Antiepileptogenic and anticonvulsant effects of NBQX, a selective AMPA receptor antagonist, in the rat kindling model of epilepsy. Brain Res. 638 36. PMID: 8199874.

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Keywords: NBQX disodium salt, supplier, water, soluble, NBQX, Glutamate, AMPA, Receptors, iGlu, Ionotropic, antagonists, AMPA Receptor Antagonists

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