R&D Systems Inc. Tocris Bioscience Boston Biochem

NBQX disodium salt

Cat. No. 1044

NBQX disodium salt C12H6N4O6SNa2 [479347-86-9]

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Chemical Name: 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide disodium salt

Biological Activity

Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo. More water soluble disodium salt of NBQX (Cat. No. 0373). Also available as part of the AMPA Receptor Tocriset™.

Licensing Information

Sold with the permission of Novo Nordisk A/S

Technical Data

M.Wt:
380.24
Formula:
C12H6N4O6SNa2
Solubility:
Soluble to 100 mM in water
Storage:
Store at -20°C
CAS No:
479347-86-9

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

References

Gill et al (1992) The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline (NBQX) in a rat focal ischaemia model. Brain Res. 580 35. PMID: 1504814.

Zeman and Lodg (1992) Pharmacological characterization of non-NMDA subtypes of glutamate receptors in the neonatal rat hemisected spinal cord in vitro. Br.J.Pharmacol. 106 367. PMID: 1382781.

Sheardown et al (1993) The pharmacology of AMPA receptors and their antagonists. Stroke 24 146. PMID: 7504337.

Namba et al (1994) Antiepileptogenic and anticonvulsant effects of NBQX, a selective AMPA receptor antagonist, in the rat kindling model of epilepsy. Brain Res. 638 36. PMID: 8199874.

If you know of a relevant citation for this product please let us know.

View Related Products by Target

Keywords: NBQX disodium salt, supplier, water, soluble, NBQX, Glutamate, AMPA, Receptors, iGlu, Ionotropic, antagonists

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