Cat. No. 3605
Chemical Name: 2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-(4-(2-pyridyl)benzyl)-9-isopropylpurine trihydrochloride
Biological ActivityInhibitor of cyclin-dependent kinase (cdk) and casein kinase 1 (CK1) (IC50 values are 0.13 μM for cdk1/cyclin B and cdk5/p25; and 0.6 μM for CK1).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Oumata et al (2008) Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1. J.Med.Chem. 51 5229. PMID: 18698753.
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Keywords: (R)-CR8, supplier, cdk1, cdk5, inhibitors, inhibits, CK1, cyclin-dependent, kinases, casein, kinase, 1
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