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(R)-CR8

Cat. No. 3605

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Chemical Name: 2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-(4-(2-pyridyl)benzyl)-9-isopropylpurine trihydrochloride

Biological Activity

Inhibitor of cyclin-dependent kinase (cdk) and casein kinase 1 (CK1) (IC₅₀ values are 0.13 μM for cdk1/cyclin B and cdk5/p25; and 0.6 μM for CK1).

Technical Data

M.Wt:

540.92

Formula:

C₂₄H₂₉N₇O.3HCl

Solubility:

Soluble to 100 mM in water and to 100 mM in DMSO

Purity:

>99 %

Storage:

Store at +4°C

CAS No:

294646-77-8

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.

Resources

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch

Safety Data Sheet: View Safety Data Sheet

References

Oumata et al (2008) Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1. J.Med.Chem. 51 5229. PMID: 18698753.

If you know of a relevant citation for this product please let us know.

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