Cat. No. 3584
Chemical Name: 6,8-Difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
Biological ActivityPotent, specific and reversible inhibitor of Golgi BFA resistance factor 1 (GBF1), an ArfGEF, that decreases Arf1 activation in vivo. Arrests secretion of soluble and membrane-associated proteins at the endoplasmic reticulum-Golgi intermediate compartment. Causes disassembly and dispersal of the Golgi and trans-Golgi network.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Certificate of Analysis / Safety Data Sheet
Saenz et al (2008) Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nature Chem.Biol. 5 157.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: Golgicide A, supplier, potent, specific, reversible, inhibitors, Golgi, BFA, resistance, factors, 1, GBF1, ArfGEF, ADP, ribosylation, factor, guanine, nucleotide, exchange
Find multiple products by catalog number
New Products in this Area
Inhibits Hedgehog signalingJervine
Inhibitor of Hedgehog (Hh) signaling; binds directly to SmoGue 1654
Selective inhibitor of OXE-R Gβγ signaling
Win a Kindle
June 15 - 18, 2013
San Francisco, CA
Booth Number: 1032