C 021 dihydrochloride
Cat. No. 3581
Chemical Name: 2-[1,4'-Bipiperidin]-1'-yl-N-cyclohep
Biological ActivityPotent CCR4 chemokine receptor antagonist (IC50 values are 0.14 and 0.039 μM for inhibition of chemotaxis in human and mouse respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Yokoyama et al (2009) Potent and orally bioavailable CCR4 antagonists: synthesis and structure-activity relationship study of 2-aminoquinazolines. Bioorg.Med.Chem. 17 64. PMID: 19081254.
If you know of a relevant citation for this product please let us know.
View Related Products by Target
Keywords: C 021 dihydrochloride, supplier, C021, dihydrochloride, potent, CCR4, chemokines, receptors, antagonists
Find multiple products by catalog number
New Products in this Area
High affinity and selective EP2 receptor antagonistSAG
Potent Smoothened receptor agonist; activates the Hedgehog signaling pathwayDC 260126
FFA1 (GPR40) antagonistAR-C 118925XX
Selective, competitive P2Y2 receptor antagonistEPPTB
Trace amine 1 (TA1) receptor antagonist/inverse agonistEPPTB
Trace amine 1 (TA1) receptor antagonist/inverse agonistNIBR 189
Potent and selective EBI2 (GPR183) receptor antagonistONO AE3 208
High affinity and selective EP4 antagonistTCS 3035
April 18 - 22, 2015