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Home »
Pharmacology » Ion Channels » Ligand-gated Ion Channels » Purinergic (P2X) Receptors » 5-BDBD
5-BDBDCat. No. 3579 |
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Chemical Name: 5-(3-Bromophenyl)-1,3-dihydro-2H-benzofuro[3,2-e]-1,4-diazepin-2-one |
Biological Activity
Potent P2X4 receptor antagonist. Blocks P2X4-mediated currents in Chinese hamster ovary cells (IC50 = 0.50 μM).Certificate of Analysis / Safety Data Sheet
Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet
References
Donnelly-Roberts et al (2008) Painful purinergic receptors. J.Pharmacol.Exp.Ther. 324 409. PMID: 18042830.
Casati et al (2011) Cell-autonomous regulation of hematopoietic stem cell cycling activity by ATP. Cell Death Differ. 18 396. PMID: 20798687.
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Keywords: 5-BDBD, supplier, potent, P2X4, antagonists, purinergic, receptors, BDBD
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