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RuBi-Glutamate

Cat No. 3574

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Chemical Name: (bis(2,2'-Bipyridine-N,N')trimethylphosphine)-(S)-1-ami nopropane-1,3-dicarboxylic acid ruthenium(2+) complex sodium hexafluorophosphate salt

Biological Activity

Ruthenium-bipyridine-triphenylphosphine caged glutamate that can be excited by visible wavelengths and releases glutamate after one- or two-photon excitation. Has high quantum efficiency and can be used at low concentrations, partly avoiding blockade of GABAergic transmission seen with other caged glutamate compounds. Display high spatial resolution and generates excitatory responses in individual dendritic spines with physiological kinetics.

Licensing Information

Sold under license from Columbia University; Patent Pending

Technical Data

M.Wt:

803.59

Formula:

C₂₈H₃₃F₆N₅NaO₄P₂Ru

Solubility:

Soluble to 20 mM in water

Storage:

Store at -20°C

The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.

Resources

Certificate of Analysis / MSDS

Certificate of Analysis: View current batch

Material Safety Data Sheet: View current batch

References

Fino et al (2009) RuBi-Glutamate: two-photon and visible-light photoactivation of neurons and dendritic spines. Front.Neural Circuits 3 1.

If you know of a useful citation for this product please let us know.

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Keywords: RuBi-Glutamate, Caged, Glutamate, mGluR, iGluR, Receptors, agonists, ionotropic, metabotropic

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